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Identity of the polymorphisms for esterase D and S-formylglutathione hydrolase in red blood cells

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Summary

The S-formylglutathione hydrolase (FGH) polymorphism of human red blood cells was studied in unrelated individuals, both by isoelectric focusing and starch gel electrophoresis, and with the substrates S-acetylglutathione and 4-methylumbelliferyl-acetate (the standard substrate for esterase D (ESD)). With both separation techniques the two substrates consistently gave similar and identically located zymograms. Thus, FGH (E.C.3.1.2.12) appears to be identical to ESD (E.C.3.1.1.1).

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Authors and Affiliations

  1. University Institute of Medical Genetics, Blegdamsvej 3, DK-2200, Copenhagen N, Denmark

    H. Eiberg & J. Mohr

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  1. H. Eiberg
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  2. J. Mohr
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Eiberg, H., Mohr, J. Identity of the polymorphisms for esterase D and S-formylglutathione hydrolase in red blood cells. Hum Genet 74, 174–175 (1986). https://doi.org/10.1007/BF00282085

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  • DOI: https://doi.org/10.1007/BF00282085

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