Abstract
Management of pharmacotherapy by the pharmacist and the general practitioner can be a difficult task in elderly patients in whom there is a high concomitant, long-term drug use. Adequate information on drug use is essential in managing pharmacotherapy as well as in an accurate assessment of drug exposure in pharmacoepidemiologic studies. In this study data from computerized pharmacy records, general-practitioner registries and home interviews with 100 elderly patients were compared. Pharmacy records contained 80% of all the prescriptions found at the home interviews, while in general-practitioner data 40% could be traced. Use of drugs dispensed long ago reduced the validity of pharmacy and general-practitioner data. Data on analgesics (70% was found) and respiratory drugs (68%) were less traceable compared to cardiovascular (83%) and psychotropic drugs (81%). Automated pharmacy records are an important source of longitudinal data on drug use and will improve the assessment of drug exposure in pharmacoepidemiologic studies and optimize pharmaceutical care.
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Jörgensen TM, Isacson DGI, Thorslund M. Prescription drug use among ambulatory elderly in a Swedish population. Ann Pharmacother 1993;27:1120–5.
Herings RMC, Heerdink ER, Bakker A. Ouderen en gecombineerd gebruik van geneesmiddelen [The elderly and concomitant use of drugs]. Pharm Weekbl 1993;128:1498–500.
Heerdink ER, Leufkens HC. Compressie en clustering van geneesmiddelengebruik bij ouderen [Compression and clustering of drug use in the elderly]. Pharm Weekbl 1993;128:1492–7.
Stewart RB, Moore MT, May FE, Marks RG, Hale WE. A longitudinal evaluation of drug use in an ambulatory elderly population. J Clin Epidemiol 1991;44:1353–9.
Christensen DB, Williams B, Goldberg HI, Martin DP, Engelberg R, LoGerfo JP. Comparison of prescription and medical records in reflecting patient antihypertensive drug therapy. Ann Pharmacother 1994;28:99–104.
West SL, Strom BL, Freundlich B, Normand E, Koch G, Savitz DA. Completeness of prescription recording in outpatient medical records from a health maintenance organization. J Clin Epidemiol 1994;47:165–71.
De Jong-van den Berg LTW, Waardenburg CM, Haaijer-Ruskamp, Dukes MNG, Wesseling H. Drug use in pregnancy: a comparative appraisal of data collecting methods. Eur J Clin Pharmacol 1993;45:9–14.
De Jong PCM, Huijsmans AA, Nienhuis HE, Nijdam WS, Zielhuis GA, Eskes TKAB. Validation of a questionnaire on medical drug use during pregnancy. Am J Epidemiol 1991;134:998–1002.
Jick H, Jick SS, Derby LE. Validation of information recorded on general practitioner based computerized data resource in the United Kingdom. BMJ 1991;302:766–8.
Price D, Cooke J, Singleton S, Freely M. Doctors' unawareness of the drugs their patients are taking: a major cause of overprescribing? BMJ 1986;292:99–100.
Strømme HK, Botten G. Physicians' perceived drug-related problems and preventive strategies concerning old patients in general practice. J Soc Admin Pharm 1992;9:172–7
Stolley PD, Tonascia JA, Sartwell PE. Agreement rates between oral anticonceptive users and prescribers in relation to drug use histories. Am J Epidemiol 1978;107:226–35.
Rosenberg MJ, Layde PM, Ory HW, Strauss JT, Rooks JB, Rubin GL. Agreement between women's histories of oral contraceptive use and physician's records. Int J Epidemiol 1980;111:389–94.
Klaukka T, Mäkelä M, Sipilä J, Martikainen J. Multiuse of prescription drugs in adults. Med Care 1993;31:445–50.
Crischilles EA. Use of medications by persons 65 and over. J Gerontol 1992;47:137–44.
Anatomical Therapeutic Chemical (ATC) classification index. Oslo: WHO Collaborating centre for drug statistics methodology, 1993.
EGRET [computer program]. Seatlle: Statistics and Epidemiology Research Corporation, 1991.
Psaty BM, Lee M, Savage PJ, Rutan GH, German PS, Lyles M. Assessing the use of medications in the elderly: methods and initial experience in the cardiovascular study. J Clin Epidemiol 1992;45:683–92.
Grymonpre RE, Sitar DS, Montgomery PR, Mitenko PA, Aoki FY. Prescribing patterns for the older heavy drug users living in the community. DICP Ann Pharmacother 1991;25:186–90.
Delafuente JC, Meuleman JR, Conlin M, Hoffman NB, Lowenthal DT. Drug use among functionally active, aged, ambulatory people. Ann Pharmacotherapy 1992;26:179–83.
Hoes AW. Non-potassium sparing diuretics and sudden death in hypertensive patients. A pharmacoepidemiologic approach [dissertation]. Rotterdam: Erasmus University, 1992.
Van Gruting CW, De Gier JJ. Medication assistance: the development of drug surveillance and drug information in the Netherlands. Ann Pharmacother 1992;26(7–8):1008–12.
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Heerdink, E.R., Leufkens, H.G., Koppedraaijer, C. et al. Information on drug use in the elderly: A comparison of pharmacy, general- practitioner and patient data. Pharm World Sci 17, 20–24 (1995). https://doi.org/10.1007/BF01875554
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DOI: https://doi.org/10.1007/BF01875554