Résumé
Le prégnénolone-16α-carbonitrile (PCN) provoque l'hypertrophie et l'hyperplasie du foie chez les rats intacts et à un moindre degré chez les rats partiellement hépatectomisés. Le nombre augmenté des mitoses des hépatocytes joue un rôle important dans l'hépatomégalie provoquée par le PCN.
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The authors wish to thank the Upjohn Company, Kalamazoo (Michigan, USA) for the PCN used in this study.
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Japundžić, M., Garg, B.D., Kovac, K. et al. Effect of pregnenolone-16α-carbonitrile on mitotic activity in the intact and regenerating rat liver. Experientia 30, 562–563 (1974). https://doi.org/10.1007/BF01926353
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DOI: https://doi.org/10.1007/BF01926353