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Inhibition of uridinediphosphate glucuronyltransferase caused by furosemide

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Summary

The diuretic agent, furosemide, inhibits liver microsomal uridinediphosphate glucuronyltransferase (EC. 2.4.1.17), in monkey and rat. Inhibition is of the non-competitive type.

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Author notes

  1. F. Sörgel & E. Mutschler

    Present address: Pharmakologisches Institut für Naturwissenschaftler, Johann-Wolfgang-von Goethe-Universität, Sandhofer Str. 75 A, D-6000, Frankfurt am Main, BRD

Authors and Affiliations

  1. Hoechst AG, P.O.B. 800320, D-6230, Frankfurt am Main 80, Federal Republic of Germany

    F. Sörgel, F. E. Beyhl & E. Mutschler

Authors
  1. F. Sörgel
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  2. F. E. Beyhl
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  3. E. Mutschler
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Sörgel, F., Beyhl, F.E. & Mutschler, E. Inhibition of uridinediphosphate glucuronyltransferase caused by furosemide. Experientia 36, 861–863 (1980). https://doi.org/10.1007/BF01978616

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  • DOI: https://doi.org/10.1007/BF01978616

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