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Cytotoxic isoquinoline alkaloids from the aerial parts ofCorydalis incisa

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Abstract

Three known isoquinoline alkaloids were isolated from the chloroform-soluble fraction of the methanolic extract of the aerial parts ofCorydalis incisa (Papaveraceae) through repeated column chromatography. Their chemical structures were elucidated as corynoline (1), corynoloxine (2) and 6-oxocorynoline (3) using spectroscopic analysis. Compounds 1-3 exhibited cytotoxicity against human A549, SK-OV-3, SK-MEL-2 and HCT15 tumor cells.

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Correspondence to Dae Keun Kim.

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Choi, S.U., Baek, Nl., Kim, SH. et al. Cytotoxic isoquinoline alkaloids from the aerial parts ofCorydalis incisa . Arch Pharm Res 30, 151–154 (2007). https://doi.org/10.1007/BF02977687

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  • DOI: https://doi.org/10.1007/BF02977687

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