Biochemical and Biophysical Research Communications
Age and gender-related gene expression of hydroxysteroid sulfotransferase-a in rat liver
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2013, Transplantation ProceedingsA gender-specific discriminator in Sprague-Dawley rat urine: The deployment of a metabolic profiling strategy for biomarker discovery and identification
2007, Analytical BiochemistryCitation Excerpt :In general, rats excrete only 20% of corticoids in their urine, the majority of these steroids are excreted in the bile and so are eliminated in the feces [44], and there is evidence that female rats [45] and mice [46] excrete more corticosteroids in the urine than do their male counterparts. This may be due, in part, to the fact that female rats have increased hydroxysteroid sulfotransferase activity [47], reported to be up to eightfold that of male rats [48,49]. This increased activity predisposes females to increased steroid sulfation and subsequent excretion via the urine.
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