Elsevier

Biochemical Pharmacology

Volume 20, Issue 12, December 1971, Pages 3353-3357
Biochemical Pharmacology

Degradation of normetanephrine and norparanephrine in human blood

https://doi.org/10.1016/0006-2952(71)90439-4Get rights and content

Abstract

Normeta- and norparanephrine disappear at similar rates when incubated with human blood. The simultaneous appearance of noradrenaline demonstrates that at least a part of this degradation is caused by O-demethylation.

Human blood seems to contain one or several enzymatic system(s) able to degrade ortho-methoxy phenols specifically.

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Present address: Institut de Botanique, Service de Microbiologie, 4000 Sart-Tilman par Liège 1, Belgium.

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