Central α2-adrenoceptors are highly stereoselective for dexmedetomidine, the dextro enantiomer of medetomidine
References (37)
- et al.
Stereoselectivity of central α-adrenoceptors involved in sleep induced by clonidine in chickens
Neurophannacology
(1985) Pupillary dilatation as an index of central nervous system α2-adrenoceptor activation
J. Pharmacol. Meth.
(1986)- et al.
Difference in applicability of the Easson-Stedman hypothesis to the α1- and α2-adrenergic effects of phenethylamines and irnida
European J. Pharmacol.
(1983) - et al.
Re-evaluation of drug-interaction with α-adrenoceptors in vivo and in vitro using imidazole derivatives
Life Sci.
(1986) - et al.
Comparison of the effects of detomidine and xylazine on some α2-adrenoceptor-mediated responses in the central nervous system
European J. Pharmacol.
(1985) - et al.
Characterization of the selectivity, specificity and potency of medetomidine as an α2-adrenoceptor agonist
European J. Pharmacol.
(1988) - et al.
Reduction in halothane requirement by clonidine, an alpha-adrenergic agonist
Anesth. Analg.
(1982) Subtypes of alpha-2 adrenergic receptors in human and ral brain
- et al.
Alpha-2A and alpha-2B adrenergic receptor subtypes: Antagonist binding in tissues and cell lines containing only one subtype
J. Pharmacol. Exp. Ther.
(1988) - et al.
Action of stereoisomers of (imidazolinyl-2)-2-benzodioxane 1–4 or 2-(2-(l,4-benzo-dioxanyl)-2-imidazoline (170 150, RX 781094) on peripheral pre-synaptic and central α2-adrenoceptors
European J. Pharmacol.
(1983)
Quantitative aspects of alpha adrenergic effects induced by clonidine-like imidazolidines. II. Central and peripheral bradycardic activities
J. Pharmacol. Exp. Ther.
(1982)
Dexmedetomidine produces a hypnotic-anesthetic action in rats via activation of central alpha-2 adrenoceptors
Anesthesiology
(1989)
CLXX. Studies on the relationsh-p between chemical constitution and physiological action. V. Molecular dissymmetry and physiological activity
Biochem. J.
(1933)
Effect of clonidine on anesthetic drug requirements and hemodynamic response during aortic surgery
Aneslhesiology
(1989)
Reduced narcotic requirement by clonidine with improved hemodynamic and adrenergic stability in patients undergoing coronary bypass surgery
Anesthesiology
(1987)
Effects of clonidine on narcotic requirements and hemodynamic response during induction of fentanyl anesthesia and endotracheal intubation
Anesthesiology
(1986)
Cloning, sequencing, and expression of the gene coding for the human platelet alpha-2 adrenergic receptor
Science
(1987)
Central α-adrenergic systems as targets for hypotensive drugs
Rev. Physiol. Biochem. Pharmacol.
(1978)
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