Estimation of glomerular filtration rate in dogs with 99M-Tc-DTPA and iohexol
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2016, August's Consultations in Feline Internal MedicineEffect of MK-467 on organ blood flow parameters detected by contrast-enhanced ultrasound in dogs treated with dexmedetomidine
2013, Veterinary Anaesthesia and AnalgesiaCitation Excerpt :However, it is excreted unmetabolized in the urine by glomerular filtration only by the kidneys and does not undergo tubular secretion or re‐absorbtion (Olsson et al. 1983). Thus, it is considered a validated marker to assess the glomerular filtration rate (Moe & Heiene 1995; Gleadhill & Michell 1996; Finco et al. 2001; Goy‐Thollot et al. 2006a,b). The primary aim of our study was to assess whether the dexmedetomidine‐induced reduction in organ blood flow could be detected by CEUS.
Glomerular filtration rate in Holstein dairy cows estimated from a single blood sample using iodixanol
2013, Journal of Dairy ScienceCitation Excerpt :Alternatively, endogenous creatinine clearance has been shown to have some advantages over inulin but is affected by other factors including active tubular secretion (Bauer et al., 1982; Darling and Morris, 1991). The nonionic, monomeric x-ray contrast medium iohexol as a GFR tracer has been used extensively in cats and dogs (Moe and Heiene, 1995; Brown et al., 1996; Von Hendy-Willson and Pressler, 2011), but concern with its use exists regarding impaired renal function (Miyamoto, 2001). Thus, efforts to find more reliable and less complicated tracers and approaches for assessing GFR are ongoing.
Estimating glomerular filtration rate in healthy dogs using inulin without urine collection
2012, Research in Veterinary ScienceCitation Excerpt :Exogenous creatinine plasma clearance may be influenced by endogenous creatinine that increases the AUC. Iohexol clearance in dogs has been reported in a number of studies (Moe and Heiene, 1995; Brown et al., 1996; Gleadhill and Michell, 1996; Finco et al., 2001; Goy-Thollot et al., 2006; Heiene et al., 2010). Although these reports suggest that iohexol is a useful indicator of the GFR, adverse effects such as iodine radiocontrast-induced nephropathy and severe hypotension have been reported in humans (Karlsberg et al., 2010; Itoh et al., 2005).