Mechanisms of halothane toxicity: Novel insights
References (138)
- et al.
The mechanism of reductive dehalogenation of halothane by liver cytochrome P-450
Biochem. Pharmac.
(1982) - et al.
Hepatic glutathione S-transferase release after halothane anaesthesia
Lancet
(1987) - et al.
Generation and detection of neoantigens in guinea pig liver slices incubated with halothane
Int. J. Immunopharmac.
(1991) - et al.
Halothane metabolism: Kupffer cells carry and partially process trifluoroacetylated protein adducts
Biochem. biophys. Res. Commun.
(1991) - et al.
Molecular cloning of the high-affinity calcium-binding protein (calreticulin) of skeletal muscle sarcoplasmic reticulum
J. biol. Chem.
(1989) Protein disulphide isomerase: multiple roles in the modification of nascent secretory proteins
Cell
(1989)- et al.
Characterization of the reactivity of autoantibodies in primary biliary cirrhosis
FEBS Lett.
(1989) - et al.
Primary biliary cirrhosis: paradigm or paradox for autoimmunity
Gastroenterology
(1991) - et al.
On the stoichiometry of the oxidase and monooxygenase reactions catalyzed by liver microsomal cytochrome P-450
J. biol. Chem.
(1984) - et al.
Screening for antibodies associated with halothane hepatitis
Br. J. Anaesth.
(1991)
Exposure to the chlorofluorocarbon substitute 2,2-dichloro-1,1,1-trifluoroethane and the anesthetic agent halothane is associated with the transient protein adduct formation in the heart
Biochem. biophys. Res. Commun.
(1992)
Carbon tetrachloride-induced lipid peroxidation dependent on an ethanol-inducible form of rabbit liver microsomal cytochrome P-450
FEBS Lett.
(1985)
T-cell tolerance by clonal elimination in the thymus
Cell
(1987)
Specific antibodies to halothane-induced liver antigens in halothane-associated hepatitis
Br. J. Anaesth.
(1987)
Purification of trifluoroacetylated protein antigens from livers of halothane-treated rats
Eur. J. Pharmac.
(1990)
The topography of trifluoroacetylated protein antigens in liver microsomal fractions from halothane treated rats
Biochem. Pharmac.
(1992)
T cell reactivity to penicillin: phenotypic analysis of in vitro activated cell subsets
J. Allergy clin. Immun.
(1986)
A metabolite of halothane covalently binds to an endoplasmic reticulum protein that is highly homologous to phosphatidylinositol-specific phosphlipase C-α but has no activity
Biochem. biophys. Res. Commun.
(1991)
Molecular cloning of dihydrolipoamide acetyltransferase of the rat pyruvate dehydrogenase complex: sequence comparison and evolutionary relationship to other dihydrolipoamide acetyltransferases
Biochem. biophys. Acta
(1992)
ERp99, an abundant, conserved glycoprotein of the endoplasmic reticulum, is homologous to the 90-kDa heat shock protein (hsp 90) and the 94-kDa glucose-regulated protein (GRP94)
J. biol. Chem.
(1987)
Subjects with a genetic defect in drug oxidation
Gastroenterology
(1983)
Theories of self tolerance and autoimmunity
Biosynthesis and biotransformation of glutathione S-conjugates to toxic metabolites
CRC Crit. Rev. Toxic.
(1988)
Human anti-endoplasmic reticulum autoantibodies appearing in a drug-induced hepatitis are directed against a human liver cytochrome P-450 that hydroxylates the drug
Basic mechanisms of adaptive immune system functions
Anti-liver endoplasmic reticulum autoantibodies are directed against human cytochrome P-450IA2
J. clin. Invest.
(1990)
Anti-liver microsomes autoantibodies and dihydralazine-induced hepatitis: specificity of autoantibodies and inductive capacity of the drug
Molec. Pharmac.
(1992)
Fulminant hepatic failure after repeated exposure to isoflurane anesthesia: a case report
Hepatology
(1991)
The calcium-binding protein calreticulin is covalently modified in rat liver by a reactive metabolite of the inhalation anesthetic halothane
Chem. Res. Toxic.
(1992)
Characterization of a halothane-induced humoral immune response in rabbits
Clin. exp. Immun.
(1987)
Circulating immune complexes in patients with fulminant hepatic failure
Gut
(1981)
Differences in biotransformation of halothane in man
Anesthesiology
(1970)
Enflurane metabolism produces covalently-bound liver adducts recognized by antibodies from patients with halothane hepatitis
Anesthesiology
(1988)
Potential metabolic basis for enflurane hepatitis and the apparent cross-sensitization between enflurane and halothane
Drug Metab. Disp.
(1988)
Halothane metabolism: immunochemical evidence for molecular mimicry of trifluoroacetylated liver protein adducts by constitutive polypeptides
Molec. Pharmac.
(1991)
Halothane metabolism: the dihydrolipoamide acetyltransferase subunit of the pyruvate dehydrogenase complex molecularly mimics trifluoroacetyl-protein adducts
Biochemistry
(1993)
Urinary metabolites of halothane in man
Anesthesiology
(1975)
Drug-specific antibodies in patients receiving captopril
Br. J. clin. Pharmac.
(1986)
Primary structure of the human M2 mitochondrial autoantigen of primary biliary cirrhosis: dihydrolipoamide acetyltransferase
Induction of benzylpenicilloyl specific antibodies including IgE by long-term administration of benzylpenicillin
Clin. Allergy
(1983)
Immunopathological mechanisms and clinical aspects of allergic reactions to drugs
Molecular mimicry in autoimmunity
Low-level binding of halothane metabolites to rat liver histones in vivo
Anesthesiology
(1981)
Nephrotoxicity of the glutathione and cysteine conjugates of 2-bromo-2-chloro-1,1-difluoroethene
J. Pharmac. exp. Ther.
(1992)
Model calculations of the relative effects of CFCs and their replacements on stratospheric ozone
Nature
(1990)
Inhibition of α-ketoglutarate dehydrogenase activity by a distinct population of autoantibodies recognizing dihydrolipoamide succinyltransferase in primary biliary cirrhosis
Hepatology
(1990)
Identification and analysis of the major M2 autoantigen in primary biliary cirrhosis
Bioactivation and covalent binding of halothane in vitro: studies with 3H- and 14C-halothane
J. Pharmac. exp. Ther.
(1980)
Identification and specificity of a cDNA encoding the 70 kDa mitochondrial antigen recognized in primary biliary cirrhosis
J. Immun.
(1987)
Protein folding in the cell
Nature
(1992)
Cited by (0)
Copyright © 1993 Published by Elsevier Inc.