Mutagenesis and comutagenesis by lead compounds
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Cited by (85)
Data Needs, Availability, Sources, and Reliability
2017, Risk Management of Complex Inorganic Materials: A Practical GuideVitamin E modifies the ultrastructure of testis and epididymis in mice exposed to lead intoxication
2013, Annals of AnatomyCitation Excerpt :In addition, children living in houses built before 1978 in the USA with lead-base water pipes or paint may have higher than normal blood lead levels (Brown and Margolis, 2012). Lead toxicity, whether occupational or otherwise, therefore, is a great concern because it has been implicated in a variety of health conditions including neurological (Perlstein and Attala, 1966; Han et al., 2007) and cancer (Roy and Rossman, 1992; Patra et al., 2001) disorders in humans. Lead toxicity has been shown to impair sperm shape and reduce the number of cells in semen (Acharya et al., 1997; Eyden et al., 1978).
Lead acetate does not inhibit dimethylnitrosamine activation and interacts with phenobarbital which is genotoxic in the ST cross of the Drosophila wing spot test
2011, Food and Chemical ToxicologyCitation Excerpt :Lead has been proven to be a major pollutant with diverse effects on living organisms (Beck, 1992; Calabrese and Baldwin, 1992; Johnson, 1998; Roy and Rossman, 1992).
Carcinogenic and genotoxic effects of lead in human populations
2011, Trace Metals and other Contaminants in the EnvironmentCitation Excerpt :DNA damage was not observed by Roy and Rossman (1992) but was seen by Robbiano et al. (1999).