Ion-exchange chromatography of nucleotides on poly-(ethyleneimine)-cellulose thin layers

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Abstract

A great number of naturally occurring mononucleotides can be separated and identified by poly(ethyleneimine)-cellulose thin-layer chromatography. RF data for 33 compounds are given, and the factors are discussed which influence the mobility under different elution conditions. The method is compared with other present techniques for separating nucleotides.

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    Supported by grants-in-aid from the U.S. Atomic Energy Commission, the U.S. Public Health Service, the National Science Foundation, and the Burroughs Wellcome Fund. This is Publication No. 1158 of the Cancer Commission of Harvard University.

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