Clinical and laboratory observationEffect of postnatal steroid administration on serum vitamin A concentrations in newborn infants with respiratory compromise
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Cited by (45)
Serum retinol levels and neonatal outcomes in preterm infants
2017, Journal of the Formosan Medical AssociationCitation Excerpt :In addition, there are various and complicated factors that affect the development of BPD and chronic lung disease and that affect retinol levels in premature infants. These include the use of antenatal steroids, the presence of inflammatory disease, and malnutrition status.6,17–21 In addition to BPD, premature infants are at risk for intraventricular hemorrhage (IVH), retinopathy of prematurity (ROP), and delayed neurological development.22–24
Vitamin A for preterm infants; where are we now?
2013, Seminars in Fetal and Neonatal MedicineCitation Excerpt :From the plethora of published data, it can be concluded that a plasma retinol concentration of <0.35 μmol/l (10 mg/dl) in a preterm infant almost certainly indicates depletion of hepatic stores, and that plasma retinol concentrations ≥0.7 μmol/l (20 μg/dl) are probably indicative of vitamin A sufficiency,25,38 at least in those infants who have not received postnatal steroids. Placental cord and infant blood concentrations of vitamin A are increased by antenatal and postnatal steroids respectively9,15,39; in the rat model this increase in serum retinol is at the expense of pulmonary and hepatic stores and is only seen in vitamin A-sufficient subjects.40 Conversely, both hepatic and pulmonary stores of vitamin A were greater in those ELBW infants who had received postnatal steroids in addition to i.m. vitamin A, compared with vitamin A-supplemented infants who had not received postnatal steroids.15
Nutritional Assessment
2011, Fetal and Neonatal Physiology E-Book, Fourth EditionVitamin A Metabolism in the Fetus and Neonate
2011, Fetal and Neonatal Physiology E-Book, Fourth EditionVitamin A Metabolism in the Fetus and Neonate
2003, Fetal and Neonatal Physiology: Third EditionNutritional Assessment
2003, Fetal and Neonatal Physiology: Third Edition