Antiviral activity of berberine and related compounds against human cytomegalovirus
Graphical abstract
Berberine chloride (1) inhibited the human cytomegalovirus replication at IC50 0.68 μM, which was equivalent to that (0.91 μM) for ganciclovir. The selectivity index of 1, the ratio of 50% cytotoxic concentration to IC50, was 110.
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