Discovery and optimization of potent and selective imidazopyridine and imidazopyridazine mTOR inhibitors
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Acknowledgments
The authors would like to acknowledge Wei Hu, Tisha San Miguel, and Leeanne Zalameda for enzyme and cell assay support. We are also grateful to Loren Berry, Xuhai Be, Liyue Huang, Meghan Langley, and Jonothan Roberts for PKDM support. Thanks to Pete Yakowec and Jin Tang for PI3Kγ expression and purification as well as Huilin Zhao and Linda Epstein for mTOR expression and purification.
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