Abstract
The reaction of pyrido[2,1-a]isoindole with maleimide derivatives has been investigated. A new rearrangement has been found, the products of which are 2-[2'-(1-R-2,5-dioxopyrrolidinidene)-2'-(1-R-2,5-dioxopyrrolidinyl)methyl]phenylpyridines. A probable mechanism for the rearrangement has been proposed. The existence of atropoisomerism for the compounds obtained has been demonstrated by 1H NMR spectra.
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Voitenko, Z.V., Pokholenko, A.A., Shkarov, O.O. et al. Cycloaddition in Condensed Isoindoles. 2. Method for Obtaining New Derivatives of 2-Phenylpyridine. Chemistry of Heterocyclic Compounds 38, 190–196 (2002). https://doi.org/10.1023/A:1015339325586
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DOI: https://doi.org/10.1023/A:1015339325586