Abstract
THE taurine conjugates of cholic and chenodeoxycholic acid1 are preponderant bile acids of murine bile. The systematic names of the bile acids referred to in the text are: taurocholic acid, 3α, 7α, 12α-trihydroxy-5β-cholanyl taurine; taurochenodeoxycholic acid, 3α,7α-dihydroxy-5β-eholanyl taurine; taurolithocholic acid, 3α-hydroxy-5β-cholanyl taurine; lithocholic acid, 3α-hydroxy-5β-cholanic acid. Although these bile acids are excreted as the sodium salts, by convention they are often referred to in the acid form. In this communication the suffix, ‘-ate’, is used to indicate the sodium salt. Intravenous administration of taurocholate to rats is known to result in increased bile flow and bile acid excretion2.
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JAVITT, N. Cholestasis in Rats induced by Taurolithocholate. Nature 210, 1262–1263 (1966). https://doi.org/10.1038/2101262a0
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DOI: https://doi.org/10.1038/2101262a0
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