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Clinical Pharmacokinetics of Doxycycline and Minocycline

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Summary

Doxycycline and minocycline are second-generation tetracyclines. They are readily absorbed, distributed throughout the organism as a function of their lipophilicity and eliminated in both the urine and the faeces. The influence of age, renal disease, malnutrition and hyperlipidaemia is reviewed, together with the main pharmacokinetic interactions.

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Saivin, S., Houin, G. Clinical Pharmacokinetics of Doxycycline and Minocycline. Clin-Pharmacokinet 15, 355–366 (1988). https://doi.org/10.2165/00003088-198815060-00001

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