A highly sensitive radiometric assay for zoxazolamine hydroxylation by liver microsomal cytochrome P-450 and P-448: properties of the membrane-bound and purified reconstituted system

Arch Biochem Biophys. 1976 Oct;176(2):788-98. doi: 10.1016/0003-9861(76)90223-x.
No abstract available

Publication types

  • Comparative Study

MeSH terms

  • Animals
  • Chromatography, High Pressure Liquid
  • Cytochrome P-450 Enzyme System / metabolism*
  • Cytochromes / metabolism*
  • Enzyme Induction / drug effects
  • Hydrogen-Ion Concentration
  • Kinetics
  • Membranes / enzymology
  • Methylcholanthrene / pharmacology
  • Microsomes, Liver / drug effects
  • Microsomes, Liver / enzymology*
  • Phenobarbital / pharmacology
  • Pregnenolone / analogs & derivatives
  • Pregnenolone / pharmacology
  • Rats
  • Tritium
  • Zoxazolamine / metabolism*

Substances

  • Cytochromes
  • Tritium
  • Methylcholanthrene
  • Pregnenolone
  • Cytochrome P-450 Enzyme System
  • Zoxazolamine
  • Phenobarbital