Optimizing drug development: strategies to assess drug metabolism/transporter interaction potential-toward a consensus

Clin Pharmacol Ther. 2001 Aug;70(2):103-14. doi: 10.1067/mcp.2001.116891.

Authors

G T Tucker¹, J B Houston, S M Huang

Affiliation

¹ Molecular Pharmacology and Pharmacogenetics, Division of Clinical Sciences, University of Sheffield, The Royal Hallamshire Hospital, UK.

PMID: 11503003
DOI: 10.1067/mcp.2001.116891

No abstract available

Publication types

Congress

MeSH terms

Animals
Biological Transport
Biotransformation
Cytochromes / antagonists & inhibitors
Drug Design*
Drug Interactions*
Drug and Narcotic Control*
Enzyme Activation
Enzyme Activators
Enzyme Induction
Enzyme Inhibitors
Humans
Metabolic Clearance Rate
Pharmacokinetics*

Substances

Cytochromes
Enzyme Activators
Enzyme Inhibitors