Further evidence that interactions between CYP2D6 and pesticide exposure increase risk for Parkinson's disease

Ann Neurol. 2004 Jun;55(6):897. doi: 10.1002/ana.20143.
No abstract available

Publication types

  • Comment
  • Comparative Study
  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Aged, 80 and over
  • Alleles
  • Case-Control Studies
  • Cytochrome P-450 CYP2D6 / genetics*
  • Cytochrome P-450 CYP2D6 / metabolism
  • Dose-Response Relationship, Drug
  • Female
  • Humans
  • Male
  • Middle Aged
  • Odds Ratio
  • Parkinson Disease / etiology*
  • Parkinson Disease / genetics
  • Pesticide Residues / toxicity*
  • Polymorphism, Restriction Fragment Length
  • RNA, Messenger / biosynthesis
  • Random Allocation
  • Reverse Transcriptase Polymerase Chain Reaction / methods
  • Risk*

Substances

  • Pesticide Residues
  • RNA, Messenger
  • Cytochrome P-450 CYP2D6