Abstract
We analyzed all the exons and exon-intron junctions of the CYP2D6 gene from 286 Japanese individuals. We detected two novel single nucleotide polymorphisms (SNPs) 2556C>T in exon 5 (Thr261Ile) and 3835A>C in exon 8 (Lys404Gln). Both these SNPs showed a frequency of 0.002.
MeSH terms
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Asian People
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Cytochrome P-450 CYP2D6 / blood
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Cytochrome P-450 CYP2D6 / genetics*
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DNA / chemistry
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DNA / isolation & purification
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Gene Frequency
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Genotype
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Humans
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Japan
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Polymorphism, Single Nucleotide*
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Sequence Analysis, DNA
Substances
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DNA
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Cytochrome P-450 CYP2D6