Abstract
Six alkaloids (1-6) have been isolated from the fruits of Evodia rutaecarpa (Juss) Benth var. bodinaieri (Dode) Huang, two of which are new compounds, identified as 2-undecyl-4(1H)-quinolone (4) and 1-methyl-2-undecanone-10'-4(1H)-quinolone (5); the known compounds were identified as rutaecarpine (1), evodiamine (2), 1-methyl-2-undecyl-4(1H)-quinoline (3) and 2-undecanone-10'-4(1H)-quinolone (6). Compounds 1-5 were evaluated for their acute toxicity.
MeSH terms
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Alkaloids / chemistry*
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Alkaloids / isolation & purification
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Alkaloids / toxicity
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Animals
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Ethanol
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Evodia / chemistry*
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Fruit / chemistry*
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Lethal Dose 50
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Magnetic Resonance Spectroscopy
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Mice
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Molecular Structure
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Plant Extracts / chemistry
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Quinolines / chemistry*
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Quinolines / isolation & purification
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Quinolines / toxicity
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Spectrophotometry
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Toxicity Tests, Acute
Substances
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1-methyl-2-undecanone-10'-4(1H)-quinolone
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2-undecyl-4(1H)-quinolone
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Alkaloids
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Plant Extracts
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Quinolines
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Ethanol