Studies on the alkaloid constituents of Evodia rutaecarpa (Juss) Benth var. bodinaieri (Dode) Huang and their acute toxicity in mice

J Asian Nat Prod Res. 2006 Dec;8(8):697-703. doi: 10.1080/10286020412331286425.

Abstract

Six alkaloids (1-6) have been isolated from the fruits of Evodia rutaecarpa (Juss) Benth var. bodinaieri (Dode) Huang, two of which are new compounds, identified as 2-undecyl-4(1H)-quinolone (4) and 1-methyl-2-undecanone-10'-4(1H)-quinolone (5); the known compounds were identified as rutaecarpine (1), evodiamine (2), 1-methyl-2-undecyl-4(1H)-quinoline (3) and 2-undecanone-10'-4(1H)-quinolone (6). Compounds 1-5 were evaluated for their acute toxicity.

Publication types

  • Comparative Study

MeSH terms

  • Alkaloids / chemistry*
  • Alkaloids / isolation & purification
  • Alkaloids / toxicity
  • Animals
  • Ethanol
  • Evodia / chemistry*
  • Fruit / chemistry*
  • Lethal Dose 50
  • Magnetic Resonance Spectroscopy
  • Mice
  • Molecular Structure
  • Plant Extracts / chemistry
  • Quinolines / chemistry*
  • Quinolines / isolation & purification
  • Quinolines / toxicity
  • Spectrophotometry
  • Toxicity Tests, Acute

Substances

  • 1-methyl-2-undecanone-10'-4(1H)-quinolone
  • 2-undecyl-4(1H)-quinolone
  • Alkaloids
  • Plant Extracts
  • Quinolines
  • Ethanol