Current progress on nucleoside antibiotics

Pharmacol Ther. 1991 Dec;52(3):269-86. doi: 10.1016/0163-7258(91)90028-k.

Abstract

Structure and biological activity of thirty-six new nucleoside antibiotics which appeared after the 1988 review are described. New synthetic analogs of neplanocin and oxetanocin are also described with special emphasis on their antiviral activities. New biosynthetic findings on nikkomycins, blasticidin S, and griseolic acid are also reviewed.

Publication types

  • Review

MeSH terms

  • Animals
  • Anti-Bacterial Agents* / chemistry
  • Anti-Bacterial Agents* / isolation & purification
  • Anti-Bacterial Agents* / therapeutic use
  • Antibiotics, Antineoplastic / chemistry
  • Antibiotics, Antineoplastic / isolation & purification
  • Antibiotics, Antineoplastic / therapeutic use
  • Antifungal Agents / chemistry
  • Antifungal Agents / isolation & purification
  • Antifungal Agents / therapeutic use
  • Humans
  • Nucleosides* / chemistry
  • Nucleosides* / isolation & purification
  • Nucleosides* / therapeutic use
  • Structure-Activity Relationship

Substances

  • Anti-Bacterial Agents
  • Antibiotics, Antineoplastic
  • Antifungal Agents
  • Nucleosides