Enhanced chiral inversion of R-ibuprofen in liver from rats treated with clofibric acid

Biochem Pharmacol. 1991 Jun 1;41(11):1775-7. doi: 10.1016/0006-2952(91)90184-7.

Authors

K M Knights¹, T F Addinall, B J Roberts

Affiliation

¹ Dept. of Clinical Pharmacology, Flinders University of South Australia, Bedford Park.

PMID: 2043167
DOI: 10.1016/0006-2952(91)90184-7

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Clofibric Acid / pharmacology*
Ibuprofen / chemistry
Ibuprofen / metabolism*
Liver / drug effects
Liver / metabolism*
Microsomes, Liver / enzymology
Rats
Stereoisomerism

Substances

Clofibric Acid
Ibuprofen