The importance of correct assignment of CYP2B6 genetic variants with respect to cyclophosphamide metabolizer status

Am J Hematol. 2011 Apr;86(4):383-4; author reply 384. doi: 10.1002/ajh.21987.
No abstract available

Publication types

  • Comment
  • Letter

MeSH terms

  • Aryl Hydrocarbon Hydroxylases / genetics*
  • Cyclophosphamide / metabolism*
  • Cyclophosphamide / pharmacokinetics
  • Cytochrome P-450 CYP2B6
  • Genotype
  • Humans
  • Metabolic Clearance Rate / genetics
  • Oxidoreductases, N-Demethylating / genetics*
  • Polymorphism, Single Nucleotide*

Substances

  • Cyclophosphamide
  • Aryl Hydrocarbon Hydroxylases
  • CYP2B6 protein, human
  • Cytochrome P-450 CYP2B6
  • Oxidoreductases, N-Demethylating