Technical desiderata for the integration of genomic data into Electronic Health Records

Daniel R Masys; Gail P Jarvik; Neil F Abernethy; Nicholas R Anderson; George J Papanicolaou; Dina N Paltoo; Mark A Hoffman; Isaac S Kohane; Howard P Levy

doi:10.1016/j.jbi.2011.12.005

Technical desiderata for the integration of genomic data into Electronic Health Records

J Biomed Inform. 2012 Jun;45(3):419-22. doi: 10.1016/j.jbi.2011.12.005. Epub 2011 Dec 27.

Authors

Daniel R Masys¹, Gail P Jarvik, Neil F Abernethy, Nicholas R Anderson, George J Papanicolaou, Dina N Paltoo, Mark A Hoffman, Isaac S Kohane, Howard P Levy

Affiliation

¹ Division of Biomedical and Health Informatics, Department of Medical Education and Biomedical Informatics, University of Washington, Seattle, WA 98195-7240, USA. dmasys@u.washington.edu

Abstract

The era of "Personalized Medicine," guided by individual molecular variation in DNA, RNA, expressed proteins and other forms of high volume molecular data brings new requirements and challenges to the design and implementation of Electronic Health Records (EHRs). In this article we describe the characteristics of biomolecular data that differentiate it from other classes of data commonly found in EHRs, enumerate a set of technical desiderata for its management in healthcare settings, and offer a candidate technical approach to its compact and efficient representation in operational systems.

Publication types

Research Support, N.I.H., Extramural

MeSH terms

Databases, Factual
Delivery of Health Care
Electronic Health Records*
Genomics*
Humans
Precision Medicine / methods*

Abstract

Publication types

MeSH terms

Grants and funding