Targeting the Achilles heel of multidrug-resistant cancer by exploiting the fitness cost of resistance

Chem Rev. 2014 Jun 11;114(11):5753-74. doi: 10.1021/cr4006236. Epub 2014 Apr 23.
No abstract available

Publication types

  • Research Support, N.I.H., Intramural
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Drug Resistance, Multiple / drug effects*
  • Humans
  • Molecular Targeted Therapy / methods*
  • Neoplasm Proteins / genetics
  • Neoplasms / drug therapy*
  • Neoplasms / genetics
  • Neoplasms / pathology

Substances

  • Neoplasm Proteins