Effect of inhibition of glutathione synthesis on the metabolism and protein conjugation of [14C]captopril in the rat

Biochem Pharmacol. 1989 Apr 1;38(7):1188-92. doi: 10.1016/0006-2952(89)90268-2.
No abstract available

MeSH terms

  • Animals
  • Captopril / metabolism*
  • Captopril / pharmacokinetics
  • Captopril / urine
  • Carrier Proteins / metabolism
  • Catalysis
  • Glutamate-Cysteine Ligase / antagonists & inhibitors*
  • Glutathione / biosynthesis*
  • Methionine / analogs & derivatives*
  • Methionine / pharmacology
  • Peptide Synthases / antagonists & inhibitors*
  • Rats
  • Tissue Distribution

Substances

  • Carrier Proteins
  • buthionine
  • Captopril
  • Methionine
  • Peptide Synthases
  • Glutamate-Cysteine Ligase
  • Glutathione