Measurement of cytochrome P-450 dependent dealkylation of alkoxyphenoxazones in hepatic S9s and hepatocyte homogenates: effects of dicumarol

Mutat Res. 1985 Mar;142(3):127-31. doi: 10.1016/0165-7992(85)90052-1.
No abstract available

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Biotransformation
  • Cytochrome P-450 CYP1A1
  • Cytochrome P-450 Enzyme System / metabolism*
  • Dicumarol / pharmacology*
  • Liver / enzymology*
  • Microsomes, Liver / metabolism
  • Oxazines / metabolism
  • Oxidoreductases / analysis*
  • Rats
  • Subcellular Fractions / enzymology

Substances

  • Oxazines
  • ethoxyresorufin
  • Dicumarol
  • Cytochrome P-450 Enzyme System
  • Oxidoreductases
  • Cytochrome P-450 CYP1A1