The pharmacology and metabolism of the thiopurine drugs 6-mercaptopurine and azathioprine

Drug Metab Rev. 1985;16(1-2):157-74. doi: 10.3109/03602538508991433.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Azathioprine / metabolism
  • Azathioprine / pharmacology*
  • Azathioprine / therapeutic use
  • Biotransformation
  • DNA / metabolism
  • DNA Replication / drug effects
  • Humans
  • Immune System Diseases / drug therapy
  • Mercaptopurine / metabolism
  • Mercaptopurine / pharmacology*
  • Mercaptopurine / therapeutic use
  • Neoplasms / drug therapy
  • Structure-Activity Relationship

Substances

  • DNA
  • Mercaptopurine
  • Azathioprine