Thioacetamide-induced hepatic necrosis. II. Pharmacokinetics of thioacetamide and thioacetamide-S-oxide in the rat

J Pharmacol Exp Ther. 1979 Mar;208(3):386-91.
No abstract available

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Acetamides / metabolism*
  • Animals
  • Chemical and Drug Induced Liver Injury / etiology
  • Chemical and Drug Induced Liver Injury / metabolism*
  • Chemical and Drug Induced Liver Injury / pathology
  • Kinetics
  • Liver / metabolism
  • Male
  • Necrosis / chemically induced
  • Necrosis / metabolism
  • Oxidation-Reduction
  • Rats
  • Sulfates / metabolism
  • Thioacetamide / analogs & derivatives
  • Thioacetamide / metabolism*
  • Thioacetamide / pharmacology
  • Tissue Distribution

Substances

  • Acetamides
  • Sulfates
  • Thioacetamide