Stimulatory effect of cigarette smoking on the hydroxylation of 3,4-benzpyrene and the N-demethylation of 3-methyl-4-monomethylaminoazobenzene by enzymes in human placenta

Clin Pharmacol Ther. 1969 Jan-Feb;10(1):100-9. doi: 10.1002/cpt1969101100.
No abstract available

MeSH terms

  • Adolescent
  • Adult
  • Animals
  • Anthracenes / pharmacology
  • Azo Compounds / pharmacology
  • Benz(a)Anthracenes / pharmacology
  • Benzopyrenes / analysis
  • Benzopyrenes / metabolism*
  • Enzyme Induction
  • Female
  • Fetus / drug effects
  • Fluorenes / pharmacology
  • Fluorescence
  • Humans
  • Maternal-Fetal Exchange / drug effects
  • Mixed Function Oxygenases / metabolism*
  • NADP / metabolism
  • Pentobarbital / metabolism
  • Phenanthrenes / pharmacology
  • Placenta / enzymology*
  • Placental Extracts / metabolism
  • Pregnancy*
  • Rats
  • Smoking*
  • Transferases / metabolism*

Substances

  • Anthracenes
  • Azo Compounds
  • Benz(a)Anthracenes
  • Benzopyrenes
  • Fluorenes
  • Phenanthrenes
  • Placental Extracts
  • NADP
  • Mixed Function Oxygenases
  • Transferases
  • Pentobarbital