Loperamide (R 18 553), a novel type of antidiarrheal agent. Part 5: the pharmacokinetics of loperamide in rats and man

MeSH terms

• Administration, Oral
• Adult
• Amides / administration & dosage
• Amides / metabolism
• Animals
• Antidiarrheals / administration & dosage
• Antidiarrheals / metabolism*
• Bile / metabolism
• Brain / metabolism
• Chlorobenzenes / administration & dosage
• Chlorobenzenes / metabolism
• Feces / analysis
• Gastrointestinal Agents / metabolism*
• Humans
• Intestinal Absorption
• Liver / metabolism
• Male
• Middle Aged
• Piperidines / administration & dosage
• Piperidines / metabolism*
• Rats
• Time Factors
• Tritium