Inhibition of phenylethanolamine N-methyltransferase by benzylamines. 2. In vitro and in vivo studies with 2,3-dichloro- -methylbenzylamine

J Med Chem. 1973 Feb;16(2):106-9. doi: 10.1021/jm00260a004.
No abstract available

MeSH terms

  • Amines / analysis
  • Amines / blood
  • Amines / chemical synthesis*
  • Animals
  • Benzyl Compounds / analysis
  • Benzyl Compounds / blood
  • Benzyl Compounds / chemical synthesis*
  • Brain Chemistry
  • Chlorine
  • Dose-Response Relationship, Drug
  • Half-Life
  • Kidney / analysis
  • Kinetics
  • Liver / analysis
  • Lung / analysis
  • Male
  • Methyltransferases / antagonists & inhibitors*
  • Myocardium / analysis
  • Phenylethanolamine N-Methyltransferase / antagonists & inhibitors
  • Rats
  • Spleen / analysis
  • Stereoisomerism
  • Structure-Activity Relationship

Substances

  • Amines
  • Benzyl Compounds
  • Chlorine
  • Methyltransferases
  • Phenylethanolamine N-Methyltransferase