Cocaine-induced hepatic necrosis in mice--the role of cocaine metabolism

Biochem Pharmacol. 1979 Aug 1;28(15):2389-95. doi: 10.1016/0006-2952(79)90705-6.
No abstract available

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Acetaminophen / pharmacology
  • Animals
  • Aspartate Aminotransferases / blood
  • Chemical and Drug Induced Liver Injury / etiology*
  • Chemical and Drug Induced Liver Injury / metabolism
  • Cocaine / metabolism
  • Cocaine / toxicity*
  • Male
  • Mice
  • Mice, Inbred Strains
  • Necrosis / chemically induced
  • Phenobarbital / pharmacology
  • Proadifen / pharmacology
  • Sleep / drug effects

Substances

  • Acetaminophen
  • Proadifen
  • Aspartate Aminotransferases
  • Cocaine
  • Phenobarbital