Reconstituted liver microsomal enzyme system that hydroxylates drugs, other foreign compounds and endogenous substrates. I. Determination of substrate specificity by the cytochrome P-450 and P-448 fractions

Biochem Biophys Res Commun. 1971 Mar 19;42(6):1200-6. doi: 10.1016/0006-291x(71)90033-7.
No abstract available

MeSH terms

  • Animals
  • Benzopyrenes / metabolism*
  • Cytochromes / metabolism*
  • Dealkylation
  • In Vitro Techniques
  • Male
  • Methylcholanthrene / pharmacology*
  • Microsomes, Liver / enzymology*
  • Microsomes, Liver / metabolism
  • Mixed Function Oxygenases / metabolism*
  • Phenethylamines / metabolism
  • Phenobarbital / pharmacology*
  • Rats

Substances

  • Benzopyrenes
  • Cytochromes
  • Phenethylamines
  • Methylcholanthrene
  • Mixed Function Oxygenases
  • Phenobarbital