Pharmacological differences between the optical isomers of ibuprofen: evidence for metabolic inversion of the (-)-isomer

J Pharm Pharmacol. 1976 Mar;28(3):256-7. doi: 10.1111/j.2042-7158.1976.tb04144.x.
No abstract available

MeSH terms

  • Acetylcholine / antagonists & inhibitors
  • Animals
  • Cattle
  • Cyclooxygenase Inhibitors
  • Erythema / drug therapy
  • Guinea Pigs
  • Ibuprofen / metabolism
  • Ibuprofen / pharmacology*
  • Ibuprofen / therapeutic use
  • In Vitro Techniques
  • Isomerism
  • Mice
  • Pain / drug therapy
  • Phenylpropionates / pharmacology*
  • Rats

Substances

  • Cyclooxygenase Inhibitors
  • Phenylpropionates
  • Acetylcholine
  • Ibuprofen