Zomepirac-induced serum sickness. A report of two cases

JAMA. 1983 May 27;249(20):2812-3.

Abstract

Two patients, after several weeks of zomepirac sodium use, experienced acute toxic eruption, fever, lymphadenopathy, arthralgias, angioedema of the hands, and eosinophilia. We believe that these cases represent type 3 allergic reactions to zomepirac.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Analgesics / adverse effects*
  • Drug Hypersensitivity / classification
  • Drug Hypersensitivity / diagnosis*
  • Humans
  • Male
  • Middle Aged
  • Pain / drug therapy
  • Pyrroles / adverse effects*
  • Serum Sickness / chemically induced*
  • Tolmetin / adverse effects*
  • Tolmetin / analogs & derivatives

Substances

  • Analgesics
  • Pyrroles
  • zomepirac
  • Tolmetin