Nephrotoxicity of p-aminophenol, a metabolite of acetaminophen, in the fischer 344 rat

Toxicol Appl Pharmacol. 1982 Sep 15;65(2):336-44. doi: 10.1016/0041-008x(82)90017-5.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Acetaminophen / metabolism*
  • Alanine Transaminase / blood
  • Aminophenols / toxicity*
  • Animals
  • Blood Urea Nitrogen
  • Isomerism
  • Kidney Diseases / chemically induced*
  • Liver / drug effects
  • Male
  • Mixed Function Oxygenases / metabolism
  • Rabbits
  • Rats
  • Rats, Inbred F344

Substances

  • Aminophenols
  • Acetaminophen
  • Mixed Function Oxygenases
  • Alanine Transaminase
  • 4-aminophenol