Studies on the in vivo and in vitro estrogenic activities of methoxychlor and its metabolites. Role of hepatic mono-oxygenase in methoxychlor activation

Biochem Pharmacol. 1978;27(20):2417-23. doi: 10.1016/0006-2952(78)90354-4.
No abstract available

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Estrogens, Non-Steroidal*
  • Female
  • Liver / enzymology*
  • Male
  • Methoxychlor / analogs & derivatives
  • Methoxychlor / metabolism
  • Methoxychlor / pharmacology*
  • Mixed Function Oxygenases / metabolism*
  • Organ Size / drug effects
  • Ornithine Decarboxylase / metabolism
  • Oxidoreductases / metabolism*
  • Proteins / metabolism
  • Rats
  • Uterus / drug effects
  • Uterus / enzymology

Substances

  • Estrogens, Non-Steroidal
  • Proteins
  • Mixed Function Oxygenases
  • Oxidoreductases
  • Ornithine Decarboxylase
  • Methoxychlor