Mechanism of the drug-metabolizing enzymes' induction by 2-diethylaminoethyl-2-2-diphenylvalerate-HCl (SKF 525 A)

Toxicol Appl Pharmacol. 1978 Nov;46(2):315-21. doi: 10.1016/0041-008x(78)90077-7.
No abstract available

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Enzyme Induction / drug effects
  • Leucine / metabolism
  • Male
  • Microsomes, Liver / drug effects
  • Microsomes, Liver / enzymology
  • Mixed Function Oxygenases / biosynthesis*
  • Oxidoreductases / biosynthesis*
  • Pentobarbital / pharmacology
  • Proadifen / pharmacology*
  • Protein Biosynthesis
  • Rats
  • Sleep / drug effects
  • Time Factors

Substances

  • Proadifen
  • Mixed Function Oxygenases
  • Oxidoreductases
  • Leucine
  • Pentobarbital