The metabolic fate of [35S]-diallyl disulphide in mice

Experientia. 1980 Aug 15;36(8):1000-1. doi: 10.1007/BF01953845.

Abstract

Diallyl disulphide (DADS) is a major constituent of garlic oil. Uptake of [35S]-labelled diallyl disulphide by mouse liver is highest at 90 min after treatment with [35S]-DADS, 70% of the radioactivity is present in the liver cytosol of which 80% is metabolized to sulphate.

MeSH terms

  • Allyl Compounds*
  • Animals
  • Disulfides / metabolism*
  • Female
  • Garlic*
  • Liver / metabolism
  • Mice
  • Plants, Medicinal*
  • Sulfur Radioisotopes

Substances

  • Allyl Compounds
  • Disulfides
  • Sulfur Radioisotopes
  • diallyl disulfide