Use of in vitro human metabolism studies in drug development. An industrial perspective

Biochem Pharmacol. 1994 Dec 16;48(12):2147-56. doi: 10.1016/0006-2952(94)00312-2.

Author

A D Rodrigues¹

Affiliation

¹ Drug Metabolism Department, Abbott Laboratories, Abbott Park, IL 60064.

PMID: 7811296
DOI: 10.1016/0006-2952(94)00312-2

No abstract available

MeSH terms

Cytochrome P-450 Enzyme Inhibitors
Cytochrome P-450 Enzyme System / metabolism
Drug Industry / methods*
Drug Interactions
Humans
In Vitro Techniques
Isoenzymes / antagonists & inhibitors
Isoenzymes / metabolism
Liver / enzymology
Models, Biological
Pharmaceutical Preparations / metabolism*
Subcellular Fractions / enzymology
Tissue Donors

Substances

Cytochrome P-450 Enzyme Inhibitors
Isoenzymes
Pharmaceutical Preparations
Cytochrome P-450 Enzyme System