Abstract
Tyr-MIF-1 previously was isolated from tissue obtained after death. A possible role of autolysis could not be excluded. We report the isolation of Tyr-MIF-1 (Tyr-Pro-Leu-Gly-NH2) in increased amounts from fresh human brain cortex. This confirms the natural existence of this brain peptide.
Publication types
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Research Support, U.S. Gov't, Non-P.H.S.
MeSH terms
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Cerebral Cortex / chemistry
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Chromatography, High Pressure Liquid
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Humans
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MSH Release-Inhibiting Hormone / analogs & derivatives*
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MSH Release-Inhibiting Hormone / isolation & purification
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Radioimmunoassay
Substances
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tyrosyl-prolyl-leucyl-glycinamide
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MSH Release-Inhibiting Hormone