Direct characterization of the selectivity of furafylline as an inhibitor of human cytochromes P450 1A1 and 1A2

Pharmacogenetics. 1994 Oct;4(5):281-4. doi: 10.1097/00008571-199410000-00007.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Cell Line
  • Cytochrome P-450 CYP1A2
  • Cytochrome P-450 Enzyme Inhibitors*
  • Humans
  • Kinetics
  • Microsomes, Liver / drug effects
  • Microsomes, Liver / enzymology
  • Oxidoreductases / antagonists & inhibitors*
  • Theophylline / analogs & derivatives*
  • Theophylline / pharmacology

Substances

  • Cytochrome P-450 Enzyme Inhibitors
  • Theophylline
  • furafylline
  • Oxidoreductases
  • Cytochrome P-450 CYP1A2