Validation and use of cloned, expressed human drug-metabolizing enzymes in heterologous cells for analysis of drug metabolism and drug-drug interactions

Biochem Pharmacol. 1993 Aug 17;46(4):559-66. doi: 10.1016/0006-2952(93)90538-8.

Authors

R P Remmel¹, B Burchell

Affiliation

¹ Department of Medicinal Chemistry, College of Pharmacy, University of Minnesota, Minneapolis 55455.

PMID: 8363629
DOI: 10.1016/0006-2952(93)90538-8

No abstract available

Publication types

Research Support, U.S. Gov't, P.H.S.
Review

MeSH terms

Animals
Catalysis
Cells, Cultured
Drug Interactions*
Enzymes / genetics
Enzymes / metabolism*
Humans
Pharmaceutical Preparations / metabolism*
Recombinant Proteins / genetics
Recombinant Proteins / metabolism

Substances

Enzymes
Pharmaceutical Preparations
Recombinant Proteins