Chlorzoxazone: an in vitro and in vivo substrate probe for liver CYP2E1

Methods Enzymol. 1996:272:115-23. doi: 10.1016/s0076-6879(96)72014-1.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Chlorzoxazone / analogs & derivatives
  • Chlorzoxazone / metabolism*
  • Cytochrome P-450 CYP2E1 / analysis
  • Cytochrome P-450 CYP2E1 / genetics
  • Cytochrome P-450 CYP2E1 / metabolism*
  • Humans
  • Hydroxylation
  • In Vitro Techniques
  • Liver / enzymology*
  • Microsomes, Liver / enzymology
  • Molecular Probes
  • Muscle Relaxants, Central / metabolism
  • Phenotype
  • Recombinant Proteins / genetics
  • Recombinant Proteins / metabolism
  • Substrate Specificity

Substances

  • Molecular Probes
  • Muscle Relaxants, Central
  • Recombinant Proteins
  • 6-hydroxychlorzoxazone
  • Cytochrome P-450 CYP2E1
  • Chlorzoxazone