Antisense oligonucleotide inhibitors for the treatment of cancer: 1. Pharmacokinetic properties of phosphorothioate oligodeoxynucleotides

Anticancer Drug Des. 1997 Jul;12(5):383-93.

Authors

R S Geary¹, J M Leeds, S P Henry, D K Monteith, A A Levin

Affiliation

¹ Isis Pharmaceuticals, Inc., Carlsbad, CA 92008, USA. rgeary@isisph.com

PMID: 9236854

No abstract available

Publication types

Review

MeSH terms

Animals
Antineoplastic Agents / pharmacokinetics*
Antineoplastic Agents / pharmacology*
Humans
Neoplasms / drug therapy
Neoplasms / metabolism
Oligonucleotides, Antisense / pharmacokinetics*
Oligonucleotides, Antisense / pharmacology*
Species Specificity
Thionucleotides / pharmacokinetics*
Thionucleotides / pharmacology*
Tissue Distribution

Substances

Antineoplastic Agents
Oligonucleotides, Antisense
Thionucleotides