Discovery of potent nonpeptide vitronectin receptor (alpha v beta 3) antagonists

J Med Chem. 1997 Jul 18;40(15):2289-92. doi: 10.1021/jm970205r.

Authors

R M Keenan¹, W H Miller, C Kwon, F E Ali, J F Callahan, R R Calvo, S M Hwang, K D Kopple, C E Peishoff, J M Samanen, A S Wong, C K Yuan, W F Huffman

Affiliation

¹ Department of Medicinal Chemistry, SmithKline Beecham Pharmaceuticals, King of Prussia, Pennsylvania 19406-0939, USA.

PMID: 9240343
DOI: 10.1021/jm970205r

No abstract available

MeSH terms

Binding Sites
Oligopeptides / chemistry
Oligopeptides / pharmacology*
Protein Conformation
Receptors, Vitronectin / antagonists & inhibitors*

Substances

Oligopeptides
Receptors, Vitronectin
arginyl-glycyl-aspartic acid